For research use only. Not for therapeutic Use.
N-(DBCO-PEG4)-N-Biotin-PEG4-NHS (Cat No.: I015884) is a multifunctional, heterobifunctional linker used in bioconjugation and labeling applications. It features a DBCO (dibenzocyclooctyne) group for copper-free click chemistry with azides, a biotin moiety for affinity capture or detection, and an NHS ester for efficient amine coupling to proteins or other biomolecules. The PEG4 spacers enhance water solubility and reduce steric hindrance, improving reaction efficiency. This reagent is ideal for site-specific labeling, pull-down assays, imaging, and creating targeted bioconjugates in chemical biology and diagnostic research.
| CAS Number | 2353409-72-8 |
| Molecular Formula | C₅₄H₇₄N₆O₁₆S |
| Purity | ≥95% |
| Target | PROTAC Linkers |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
