N-Denitroso-N’-nitroso Lomustine

• CAT Number: R053518
• CAS Number: 54749-91-6
• Molecular Formula: C9H16ClN3O2
• Molecular Weight: 233.69
• Purity: ≥95%
• Synonyms: N’-(2-Chloroethyl)-N-cyclohexyl-N-nitrosourea
• Storage: Store at -20°C
• IUPAC Name: 3-(2-chloroethyl)-1-cyclohexyl-1-nitrosourea
• InChI: InChI=1S/C9H16ClN3O2/c10-6-7-11-9(14)13(12-15)8-4-2-1-3-5-8/h8H,1-7H2,(H,11,14)
• InChIKey: IGMMTYZWNUSEEU-UHFFFAOYSA-N
• SMILES: C1CCC(CC1)N(C(=O)NCCCl)N=O

N-Denitroso-N’-nitroso lomustine（Cat No.:R053518）, is a chemical compound used primarily in cancer treatment. It is a member of the nitrosourea class of drugs. This compound is a yellow crystalline powder with the ability to cross the blood-brain barrier, making it effective against brain tumors, particularly gliomas. It exerts its anticancer effects by damaging DNA, inhibiting cell division, and inducing apoptosis in cancer cells. However, its use is associated with potential side effects, including bone marrow suppression and liver toxicity.