For research use only. Not for therapeutic Use.
N-Desacetyl-N-formyl Apremilast (CAT: C000622) is an impurity found in Apremilast, which is an oral phosphodiesterase 4 (PDE4) inhibitor used in the treatment of psoriatic arthritis and certain other inflammatory conditions. Impurities like N-Desacetyl-N-formyl Apremilast are closely monitored in pharmaceutical manufacturing to ensure the purity and safety of the final drug product. Apremilast’s mechanism of action involves inhibiting PDE4, which in turn helps modulate inflammatory responses in conditions like psoriatic arthritis.
Catalog Number | C000622 |
CAS Number | 2077897-94-8 |
Synonyms | N-[2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-formamide; |
Molecular Formula | C₂₁H₂₂N₂O₇S |
Purity | ≥95% |
Solubility | Chloroform (Sparingly), Methanol (Slightly) |
Appearance | White to Off-White Solid |
Storage | -20°C, Inert atmosphere |
Reference | Gan, E., et al.: BioDrugs, 27, 359 (2013); Pathan, E., et al.: Annal. Rheum. DIs., 72, 1475 (2013); Xiong, K., et al.: Anal. Methods, 8, 1889 (2016); |