N-Desethyl N-Methyl Rivastigmine

• CAT Number: C000772
• CAS Number: 1230021-28-9
• Molecular Formula: C₁₃H₂₀N₂O₂
• Molecular Weight: 236.32
• Purity: ≥95%
• Synonyms: N,​N-Ddimethyl-carbamic Acid 3-​[(1S)​-​1-​(Dimethylamino)​ethyl]​phenyl Ester; Rivastigmine EP Impurity B
• Solubility: Chloroform (Slightly), Dichloromethane (Slightly, Heated, Sonicated), Methanol (
• Appearance: Colourless to Pale Yellow Oil
• Storage: -20°C
• IUPAC Name: [3-[(1S)-1-(dimethylamino)ethyl]phenyl] N,N-dimethylcarbamate
• InChI: InChI=1S/C13H20N2O2/c1-10(14(2)3)11-7-6-8-12(9-11)17-13(16)15(4)5/h6-10H,1-5H3/t10-/m0/s1
• InChIKey: AIHREYCBCYOMLZ-JTQLQIEISA-N
• SMILES: CC(C1=CC(=CC=C1)OC(=O)N(C)C)N(C)C

N-Desethyl N-Methyl rivastigmine (Cat No.:C000772) is a chemical compound derived from rivastigmine, a medication used to treat Alzheimer’s disease and Parkinson’s disease. This derivative likely plays a role in pharmacological research and drug metabolism studies. The removal of the ethyl and methyl groups may impact its pharmacological properties. Researchers may explore its interactions with cholinesterase enzymes, neurotransmitter pathways, and potential therapeutic applications. Investigations into its effects on cognitive function, memory, and motor skills could provide insights into its role in neurodegenerative disorders, potentially leading to the development of novel treatments for Alzheimer’s disease and Parkinson’s disease.

Reference

Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),