For research use only. Not for therapeutic Use.
N-Desethyl vardenafil is the major metabolite of Vardenafil (HY-B0442) and can be detected in human urine[1][2].
| Catalog Number | R006137 |
| CAS Number | 448184-46-1 |
| Synonyms | 2-(2-ethoxy-5-piperazin-1-ylsulfonylphenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one |
| Molecular Formula | C21H28N6O4S |
| Purity | ≥95% |
| InChI | InChI=1S/C21H28N6O4S/c1-4-6-18-23-14(3)19-21(28)24-20(25-27(18)19)16-13-15(7-8-17(16)31-5-2)32(29,30)26-11-9-22-10-12-26/h7-8,13,22H,4-6,9-12H2,1-3H3,(H,24,25,28) |
| InChIKey | OKUKNGDVADFTHE-UHFFFAOYSA-N |
| SMILES | CCCC1=NC(=C2N1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCNCC4)OCC)C |
| Reference | [1]. Bartošová Z, et al. High-performance liquid chromatographic method with amperometric detection employing boron-doped diamond electrode for the determination of sildenafil, vardenafil and their main metabolites in plasma. J Chromatogr A. 2011 Nov 4;1218(44):7996-8001. [2]. Strano-Rossi S, et al. A gas chromatography/mass spectrometry method for the determination of sildenafil, vardenafil and tadalafil and their metabolites in human urine. Rapid Commun Mass Spectrom. 2010 Jun 15;24(11):1697-706. |
