N-Deshydroxyethyl Dasatinib-d8

• CAT Number: R008571
• CAS Number: 1189998-96-6
• Molecular Formula: C20H22ClN7OS
• Molecular Weight: 452.00
• Purity: ≥95%
• Synonyms: N-(2-Chloro-6-methylphenyl)-2-[[2-methyl-6-(1-piperazinyl-d8)-4-pyrimidinyl]amino]-5-thiazolecarboxamide; Dasatinib Metabolite M4-d8
• Storage: Store at -20°C
• IUPAC Name: N-(2-chloro-6-methylphenyl)-2-[[2-methyl-6-(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)pyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide
• InChI: InChI=1S/C20H22ClN7OS/c1-12-4-3-5-14(21)18(12)27-19(29)15-11-23-20(30-15)26-16-10-17(25-13(2)24-16)28-8-6-22-7-9-28/h3-5,10-11,22H,6-9H2,1-2H3,(H,27,29)(H,23,24,25,26)/i6D2,7D2,8D2,9D2
• InChIKey: DOBZFFWLHXORTB-COMRDEPKSA-N
• SMILES: [2H]C1(C(N(C(C(N1)([2H])[2H])([2H])[2H])C2=NC(=NC(=C2)NC3=NC=C(S3)C(=O)NC4=C(C=CC=C4Cl)C)C)([2H])[2H])[2H]

N-Deshydroxyethyl Dasatinib-d8(CAT: R008571) is a deuterium-labeled derivative of the metabolite N-Deshydroxyethyl Dasatinib, designed for advanced pharmaceutical and analytical research. Incorporating eight deuterium atoms, this isotopically labeled compound is ideal for studying dasatinib metabolism, pharmacokinetics, and drug-drug interactions through highly accurate mass spectrometry and isotopic tracer techniques. Its enhanced stability and specificity make it a critical tool for identifying metabolic pathways and optimizing therapeutic strategies. N-Deshydroxyethyl Dasatinib-d8 is an invaluable resource for researchers engaged in drug development and precision medicine.