(+)-N-Desmethyl Tramadol-d3

• CAT Number: R025362
• CAS Number: 1261395-92-9
• Molecular Formula: C15H23NO2
• Molecular Weight: 252.372
• Purity: ≥95%
• Synonyms: (1R,2R)-(+)-1-(3-Methoxyphenyl)-2-[(methylamino)methyl]-cyclohexanol-d3;?cis-(+)-1-(3-Methoxyphenyl)-2-[(methylamino)methyl]-cyclohexanol-d3
• Storage: -20°C
• IUPAC Name: (1R,2R)-1-(3-methoxyphenyl)-2-[(trideuteriomethylamino)methyl]cyclohexan-1-ol
• InChI: InChI=1S/C15H23NO2/c1-16-11-13-6-3-4-9-15(13,17)12-7-5-8-14(10-12)18-2/h5,7-8,10,13,16-17H,3-4,6,9,11H2,1-2H3/t13-,15+/m1/s1/i1D3
• InChIKey: VUMQHLSPUAFKKK-RSGFOGQCSA-N
• SMILES: [2H]C([2H])([2H])NC[C@H]1CCCC[C@@]1(C2=CC(=CC=C2)OC)O

(+)-N-Desmethyl Tramadol-d3 is a deuterated form of (+)-N-desmethyl tramadol, a metabolite of the analgesic tramadol. The three deuterium atoms replace hydrogen atoms in the molecule, facilitating enhanced tracking of its pharmacokinetics and metabolic pathways. This isotopic labeling helps researchers study the compound’s absorption, distribution, metabolism, and excretion with greater precision. It is particularly useful in pharmacokinetic studies to optimize dosage regimens and understand the metabolite’s role in the overall efficacy and safety profile of tramadol. The detailed data obtained assists in improving therapeutic strategies and drug development.