N-Ethyl Maleimide

• CAT Number: R046254
• CAS Number: 128-53-0
• Molecular Formula: C6H7NO2
• Molecular Weight: 125.13
• Purity: ≥95%
• Synonyms: 1-Ethyl-1H-pyrrole-2,5-dione; 1-Ethyl-1H-pyrrole-2,5-dione; Ethylmaleimide; Maleic Acid N-Ethylimide; NEM; NSC 7638
• Target: Cell Cycle/DNA Damage
• Storage: -20°C
• IUPAC Name: 1-ethylpyrrole-2,5-dione
• InChI: InChI=1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3
• InChIKey: HDFGOPSGAURCEO-UHFFFAOYSA-N
• SMILES: CCN1C(=O)C=CC1=O

N-Ethyl Maleimide(Cat No.:R046254) is a chemical compound commonly used in biochemical and molecular biology research. It is an alkylating agent that reacts with sulfhydryl (-SH) groups in proteins and other biomolecules, leading to the formation of covalent bonds. This property makes it useful for modifying and cross-linking proteins, studying protein structure and function, and investigating enzyme mechanisms. N-Ethyl Maleimide is often employed in experiments to selectively block or inhibit the activity of cysteine residues in proteins. Its reactivity with sulfhydryl groups has made it a valuable tool in understanding various biological processes and interactions.