N-Formyl Erythromycin A (>90%)

• CAT Number: C000397
• CAS Number: 127955-44-6
• Molecular Formula: C₃₇H₆₅NO₁₄
• Molecular Weight: 747.91
• Purity: ≥95%
• Synonyms: N-Demethyl-N-formylerythromycin; Oxacyclotetradecane, Erythromycin Derivative; N-((2S,3R,4S,6R)-2-(((3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-Trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl)oxy)-3-hydroxy-6-methyltetrahydro-2H-pyran-4-yl)-N-methylformamide
• Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• Appearance: White to Off-White Solid
• Storage: -20°C
• IUPAC Name: N-[(2S,3R,4S,6R)-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-oxacyclotetradec-6-yl]oxy]-3-hydroxy-6-methyloxan-4-yl]-N-methylformamide
• InChI: InChI=1S/C37H65NO14/c1-13-25-37(10,46)30(42)20(4)27(40)18(2)15-35(8,45)32(52-34-28(41)24(38(11)17-39)14-19(3)48-34)21(5)29(22(6)33(44)50-25)51-26-16-36(9,47-12)31(43)23(7)49-26/h17-26,28-32,34,41-43,45-46H,13-16H2,1-12H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
• InChIKey: GTUJGRXTLVETBU-RWJQBGPGSA-N
• SMILES: CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C=O)O)(C)O)C)C)O)(C)O

N-Formyl Erythromycin A(CAT: C000397) is a specialized derivative of erythromycin, functioning as a macrolide antibiotic inhibitor targeting bacterial protein synthesis. This compound binds to the 50S ribosomal subunit, interfering with peptide elongation by preventing the translocation of tRNA molecules. Its precise mechanism of action and high specificity make it an essential tool in microbiology and infectious disease research, particularly for studying bacterial resistance mechanisms and ribosomal function. N-Formyl Erythromycin A finds its most significant application within anti-infective pharmaceutical research, serving as a critical reference compound for developing next-generation antibiotics and understanding bacterial adaptation pathways in response to therapeutic interventions.