N-Formyl N,N-Didesmethyl Sibutramine-d6

• CAT Number: R011493
• CAS Number: 1185163-48-7
• Molecular Formula: C16H22ClNO
• Molecular Weight: 285.845
• Purity: ≥95%
• Synonyms: {N-[1-(4-Chlorophenyl)cyclobutyl-d6]-3-methylbutyl}formamide
• Storage: Desiccate at RT
• IUPAC Name: N-[1-[1-(4-chlorophenyl)-2,2,3,3,4,4-hexadeuteriocyclobutyl]-3-methylbutyl]formamide
• InChI: InChI=1S/C16H22ClNO/c1-12(2)10-15(18-11-19)16(8-3-9-16)13-4-6-14(17)7-5-13/h4-7,11-12,15H,3,8-10H2,1-2H3,(H,18,19)/i3D2,8D2,9D2
• InChIKey: IYVDPOSYKKHSFG-QYDDHRNTSA-N
• SMILES: [2H]C1(C(C(C1([2H])[2H])(C2=CC=C(C=C2)Cl)C(CC(C)C)NC=O)([2H])[2H])[2H]

N-Formyl N,N-Didesmethyl Sibutramine-d6 is a deuterated analog of a key metabolite of sibutramine, featuring six deuterium atoms. This isotopically labeled compound is crucial in pharmaceutical research, particularly in the study of sibutramine’s metabolic pathways, pharmacokinetics, and drug-drug interactions. The deuterium labeling allows for enhanced sensitivity and precision in mass spectrometry, facilitating the accurate quantification of this metabolite in biological samples. N-Formyl N,N-Didesmethyl Sibutramine-d6 is indispensable for researchers investigating the safety, efficacy, and metabolic profile of sibutramine and its derivatives. Its high purity and stability make it a reliable choice for advanced analytical studies.