N-Hydroxy-2-aminofluorene

• CAT Number: C000993
• CAS Number: 53-94-1
• Molecular Formula: C₁₃H₁₁NO
• Molecular Weight: 197.23
• Purity: ≥95%
• Synonyms: N-Hydroxy-9H-fluoren-2-amine; 2-(Hydroxyamino)fluorene; N-2-Fluorenylhydroxylamine; N-Hydroxy-2-aminofluorene; N-Hydroxy-2-fluorenamine
• Solubility: DMSO (Slightly), Ethyl Acetate (Slightly)
• Appearance: Light Yellow to Yellow Solid
• Storage: -20°C
• IUPAC Name: N-(9H-fluoren-2-yl)hydroxylamine
• InChI: InChI=1S/C13H11NO/c15-14-11-5-6-13-10(8-11)7-9-3-1-2-4-12(9)13/h1-6,8,14-15H,7H2
• InChIKey: JJCLXJPUTJMRTM-UHFFFAOYSA-N
• SMILES: C1C2=CC=CC=C2C3=C1C=C(C=C3)NO

N-Hydroxy-2-aminofluorene（Cat No.:C000993）, is a synthetic organic compound and a member of the aromatic amines family. It is a white to off-white solid. The compound is used in research and toxicology studies as a model substrate to study the role of N-hydroxy arylamines in chemical carcinogenesis. N-Hydroxy-2-aminofluorene is metabolically activated to form a potent carcinogenic electrophile, making it valuable for understanding the molecular mechanisms of cancer development.

Reference

Guo, Z. et al.: Chem. Res. Toxicol., 17, 275 (2004);