N-Isopropylacrylamide

For research use only. Not for therapeutic Use.

  • CAT Number: M012255
  • CAS Number: 2210-25-5
  • Molecular Formula: C6H11NO
  • Molecular Weight: 113.16
  • Purity: ≥95%
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Catalog Number M012255
CAS Number 2210-25-5
Synonyms

AKOS 91289;Isopropyl acrylamide;ISOPROPYLACRYLAMIDE(N-);N-ISOPROPYLACRYLAMIDE;NIPAM;2-Propenamide, N-(1-methylethyl)-;Isopropylamid kyseliny akrylove;isopropylamidkyselinyakrylove

Molecular Formula C6H11NO
Purity ≥95%
Storage -20°C
IUPAC Name N-propan-2-ylprop-2-enamide
InChI InChI=1S/C6H11NO/c1-4-6(8)7-5(2)3/h4-5H,1H2,2-3H3,(H,7,8)
InChIKey QNILTEGFHQSKFF-UHFFFAOYSA-N
SMILES CC(C)NC(=O)C=C
Reference

1: Wang Z, Lam WY, Pelton R. N-chlorinated poly(N-isopropylacrylamide) microgels.
Langmuir. 2013 Oct 22;29(42):12924-9. doi: 10.1021/la403229g. Epub 2013 Oct 10.
PubMed PMID: 24073763.

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2: Zhang Y, Teo BM, Goldie KN, St&#228;dler B.
Poly(N-isopropylacrylamide)/poly(dopamine) capsules. Langmuir. 2014 May
20;30(19):5592-8. doi: 10.1021/la5005227. Epub 2014 May 6. PubMed PMID: 24761831.
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3: de Sousa A, de Sousa EM, de Sousa RG. Synthesis and Characterization of
Poly(N-isopropylacrylamide)/SBA-15 Silica Nanocomposites. J Nanosci Nanotechnol.
2015 Dec;15(12):9438-48. PubMed PMID: 26682364.
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4: Alexander A, Ajazuddin, Khan J, Saraf S, Saraf S. Polyethylene glycol
(PEG)-Poly(N-isopropylacrylamide) (PNIPAAm) based thermosensitive injectable
hydrogels for biomedical applications. Eur J Pharm Biopharm. 2014
Nov;88(3):575-85. doi: 10.1016/j.ejpb.2014.07.005. Epub 2014 Aug 1. Review.
PubMed PMID: 25092423.
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5: Spasojevi&#263; M, Vorenkamp J, Jansen MRPACS, de Vos P, Schouten AJ. Synthesis and
Phase Behavior of Poly(N-isopropylacrylamide)-b- Poly(L-Lysine Hydrochloride) and
Poly(N-Isopropylacrylamide- co-Acrylamide)-b-Poly(L-Lysine Hydrochloride).
Materials (Basel). 2014 Jul 22;7(7):5305-5326. doi: 10.3390/ma7075305. PubMed
PMID: 28788130; PubMed Central PMCID: PMC5455825.
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6: Kj&#248;niksen AL, Calejo MT, Zhu K, Cardoso AM, de Lima MC, Jurado AS, Nystr&#246;m B,
Sande SA. Sustained release of naltrexone from poly(n-isopropylacrylamide)
microgels. J Pharm Sci. 2014 Jan;103(1):227-34. doi: 10.1002/jps.23780. Epub 2013
Nov 11. PubMed PMID: 24218151.

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7: Li X, Zhong H, Li X, Jia F, Cheng Z, Zhang L, Yin J, An L, Guo L. Synthesis of
attapulgite/N-isopropylacrylamide and its use in drug release. Mater Sci Eng C
Mater Biol Appl. 2014 Dec;45:170-5. doi: 10.1016/j.msec.2014.08.056. Epub 2014
Sep 6. PubMed PMID: 25491816.

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