N-Methylmesoporphyrin IX

• CAT Number: M127268
• CAS Number: 142234-85-3
• Molecular Formula: C35H40N4O4
• Molecular Weight: 580.72
• Purity: ≥95%
• Synonyms: 3-[18-(2-carboxyethyl)-7,12-diethyl-3,8,13,17,22-pentamethyl-23H-porphyrin-2-yl]propanoic acid
• InChI: InChI=1S/C35H40N4O4/c1-8-22-18(3)26-14-27-19(4)24(10-12-34(40)41)29(36-27)15-30-25(11-13-35(42)43)20(5)28(38-30)16-33-23(9-2)21(6)32(39(33)7)17-31(22)37-26/h14-17,37H,8-13H2,1-7H3,(H,40,41)(H,42,43)
• InChIKey: XODZICXILWCPBD-UHFFFAOYSA-N
• SMILES: CCC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5C)C=C1N2)C)CC)C(=C4CCC(=O)O)C)C(=C3C)CCC(=O)O)C

N-Methylmesoporphyrin IX（Cat No.:M127268）is a synthetic porphyrin derivative known for its ability to selectively bind to G-quadruplex DNA structures, which are four-stranded configurations found in telomeres and gene promoter regions. By stabilizing these structures, N-Methylmesoporphyrin IX interferes with processes such as replication and transcription, making it a valuable tool in cancer research and molecular biology. It is also used as a fluorescent probe for studying nucleic acid structures and dynamics. Its high affinity and specificity for G-quadruplexes make it useful in exploring therapeutic strategies targeting genomic stability and oncogene regulation.