For research use only. Not for therapeutic Use.
N-Nitrosomorpholine-d8 is deuterium labeled N-Nitrosomorpholine. N-Nitrosomorpholine is a nitrosamine that is sensitive to light. N-nitrosomorpholine is a strong animal carcinogen[1].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
| Catalog Number | M071923 |
| CAS Number | 1219805-76-1 |
| Synonyms | 2,2,3,3,5,5,6,6-octadeuterio-4-nitrosomorpholine |
| Molecular Formula | C4D8N2O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C4H8N2O2/c7-5-6-1-3-8-4-2-6/h1-4H2/i1D2,2D2,3D2,4D2 |
| InChIKey | ZKXDGKXYMTYWTB-SVYQBANQSA-N |
| SMILES | C1COCCN1N=O |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. K D Brunnemann, et al. N-Nitrosomorpholine and Other Volatile N-nitrosamines in Snuff Tobacco. Carcinogenesis. 1982;3(6):693-6. |
