For research use only. Not for therapeutic Use.
N-Norbimatoprost(Cat No.:R034366)is a synthetic prostaglandin analog used primarily in ophthalmology to treat glaucoma and ocular hypertension. It functions by increasing the outflow of aqueous humor, thereby reducing intraocular pressure. Structurally similar to Bimatoprost but without the N-ethyl group, N-Norbimatoprost maintains potent efficacy with potentially altered pharmacokinetic properties. Its effectiveness in lowering eye pressure helps prevent optic nerve damage and vision loss. Research into N-Norbimatoprost also explores its applications in promoting eyelash growth, highlighting its versatility and importance in both therapeutic and cosmetic contexts.
Catalog Number | R034366 |
CAS Number | 155205-89-3 |
Synonyms | Bimatoprost amide;17-phenyl trinor PGF2α amide |
Molecular Formula | C23H33NO4 |
Purity | ≥95% |
Target | Drug Metabolite |
Storage | -20°C |
IUPAC Name | (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enamide |
InChI | InChI=1S/C23H33NO4/c24-23(28)11-7-2-1-6-10-19-20(22(27)16-21(19)26)15-14-18(25)13-12-17-8-4-3-5-9-17/h1,3-6,8-9,14-15,18-22,25-27H,2,7,10-13,16H2,(H2,24,28)/b6-1-,15-14+/t18-,19+,20+,21-,22+/m0/s1 |
InChIKey | RAGQWYIPCPFTJC-KDACTHKWSA-N |
SMILES | C1C(C(C(C1O)C=CC(CCC2=CC=CC=C2)O)CC=CCCCC(=O)N)O |