N-Succinimidyl Iodoacetate

• CAT Number: R000692
• CAS Number: 39028-27-8
• Molecular Formula: C6H6INO4
• Molecular Weight: 283.02
• Purity: ≥95%
• Synonyms: N-Iodoacetoxysuccinimide; N-Hydroxysuccinimidyl Iodoacetate; N-Hydroxysuccinimide Iodoacetic Acid Ester
• Target: ADC Linker
• Storage: Store at -20°C
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 2-iodoacetate
• InChI: InChI=1S/C6H6INO4/c7-3-6(11)12-8-4(9)1-2-5(8)10/h1-3H2
• InChIKey: VRDGQQTWSGDXCU-UHFFFAOYSA-N
• SMILES: C1CC(=O)N(C1=O)OC(=O)CI

N-Succinimidyl Iodoacetate（Cat No.:R000692）, is a reactive compound used in bioconjugation and protein labeling. It contains a succinimidyl ester group that enables the covalent attachment of the compound to primary amines in proteins or peptides. N-Succinimidyl Iodoacetate is specifically designed for thiol-specific labeling, targeting cysteine residues. The reaction forms stable thioether bonds, allowing for efficient protein modification. It finds applications in protein labeling, site-specific conjugation, and immobilization of biomolecules.