N-(tert-Butoxycarbonyl)-N-methyl-D-leucine

• CAT Number: I043141
• CAS Number: 89536-84-5
• Molecular Formula: C12H23NO4
• Molecular Weight: 245.32
• Purity: ≥95%
• Synonyms: (2R)-4-methyl-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]pentanoic acid
• InChI: InChI=1S/C12H23NO4/c1-8(2)7-9(10(14)15)13(6)11(16)17-12(3,4)5/h8-9H,7H2,1-6H3,(H,14,15)/t9-/m1/s1
• InChIKey: YXJFAOXATCRIKU-SECBINFHSA-N
• SMILES: CC(C)C[C@H](C(=O)O)N(C)C(=O)OC(C)(C)C

N-(tert-Butoxycarbonyl)-N-methyl-D-leucine（Cat No.:I043141）is a modified derivative of D-leucine, where a tert-butoxycarbonyl (Boc) group is attached to the amino group, and a methyl group is added to the nitrogen atom at the N-terminal position. The Boc group acts as a protective group, preventing unwanted reactions during peptide synthesis and can be removed under mild acidic conditions. The N-methylation at the nitrogen introduces steric hindrance, potentially influencing the compound’s conformation and its interaction with enzymes or receptors. This derivative is used in peptide synthesis and studies involving modified amino acids.