For research use only. Not for therapeutic Use.
N1-Methyl-2′-deoxyadenosine, DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Catalog Number | I041363 |
| CAS Number | 60192-55-4 |
| Synonyms | (2R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methylpurin-9-yl)oxolan-3-ol |
| Molecular Formula | C11H15N5O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C11H15N5O3/c1-15-4-14-11-9(10(15)12)13-5-16(11)8-2-6(18)7(3-17)19-8/h4-8,12,17-18H,2-3H2,1H3/t6?,7-,8-/m1/s1 |
| InChIKey | AYVJNJNKPVUEGT-SPDVFEMOSA-N |
| SMILES | CN1C=NC2=C(C1=N)N=CN2C3CC(C(O3)CO)O |
| Reference | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
