N1,N12-Diacetylspermine Dihydrochloride

• CAT Number: R014045
• CAS Number: 77928-71-3
• Molecular Formula: C14H32Cl2N4O2
• Molecular Weight: 359.34
• Purity: ≥95%
• Synonyms: N,N’-[1,4-butanediylbis(imino-3,1-propanediyl)]bis-acetamide Dihydrochloride; BAS; N,N’-[Tetramethylenebis(iminotrimethylene)]bis-acetamide Dihydrochloride; N1,N12-Bis(acetyl)spermine Dihydrochloride
• Target: Endogenous Metabolite
• Storage: -20°C
• IUPAC Name: N-[3-[4-(3-acetamidopropylamino)butylamino]propyl]acetamide;dihydrochloride
• InChI: InChI=1S/C14H30N4O2.2ClH/c1-13(19)17-11-5-9-15-7-3-4-8-16-10-6-12-18-14(2)20;;/h15-16H,3-12H2,1-2H3,(H,17,19)(H,18,20);2*1H
• InChIKey: NQNXERHVLXYXRO-UHFFFAOYSA-N
• SMILES: CC(=O)NCCCNCCCCNCCCNC(=O)C.Cl.Cl

N1,N12-Diacetylspermine Dihydrochloride(CAT: R014045) is a synthetic derivative of the naturally occurring polyamine, spermine. It is characterized by the acetylation of the primary amino groups at the N1 and N12 positions, and it is provided as a dihydrochloride salt to enhance stability and solubility. This compound is commonly used in biochemical research, particularly in the study of polyamine metabolism and cancer biomarkers, as elevated levels of diacetylated spermine derivatives have been observed in certain cancers. Additionally, it is useful for exploring cellular growth, differentiation, and apoptosis pathways, as polyamines like spermine play essential roles in regulating these biological processes.