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N1,N2-bis[1-[4-[[[(4-Fluorophenyl)methyl]amino]carbonyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-pyrimidinyl]-1-methylethyl]ethanediamide (>85%)
For research use only. Not for therapeutic Use.
N1,N2-bis[1-[4-[[[(4-Fluorophenyl)methyl]amino]carbonyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-pyrimidinyl]-1-methylethyl]ethanediamide (CAT: C000205) is an impurity that can be found in the synthesis of Raltegravir Potassium, a potent inhibitor of human immunodeficiency virus (HIV) integrase. Raltegravir is recognized as a novel anti-AIDS drug and acts by inhibiting the integration of viral DNA into the host genome, a crucial step in the replication of HIV. This compound, through its unique mechanism of action, contributes to the suppression of viral replication and the management of HIV infection.
Catalog Number | C000205 |
CAS Number | 1391918-18-5 |
Molecular Formula | C₃₄H₃₆F₂N₈O₈ |
Purity | ≥95% |
Solubility | DMF (Slightly), DMSO (Slightly) |
Appearance | Pale Red Solid |
Storage | -20°C, Inert atmosphere |
Reference | Wade, K., et al.: J. Pharmacol. Biomed. Anal., 8, 401 (1990), Hazuda, D., et al.: Science, 287, 646 (2000), Williams, J., et al.: Drug Metab. Dispos., 32, 1201 (2004), Duckett, C., et al.: Xenobiotica, 36, 59 (2006), Miners, J., et al.: Biochem. Pharmacol., 71, 1531 (2006), Summa, V., et al.: J. Med. Chem., 49, 6646 (2006), |