N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite

For research use only. Not for therapeutic Use.

  • CAT Number: L010777
  • CAS Number: 105931-57-5
  • Molecular Formula: C47H54N5O8P
  • Molecular Weight: 847.90
  • Purity: ≥95%
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N4-Benzoyl-2′-deoxy-5′-O-DMT-5-methylcytidine 3′-CE phosphoramidite(Cat No.:L010777)is a chemically modified nucleoside used in oligonucleotide synthesis. The N4-benzoyl and 5′-O-DMT (dimethoxytrityl) protective groups ensure stability during the synthesis process, while the 3′-CE (cyanoethyl) phosphoramidite group enables efficient incorporation into DNA strands. This modified nucleoside is particularly valuable for producing methylated DNA, which is important in studying epigenetic regulation and DNA-protein interactions. It is commonly used in research involving gene expression, DNA methylation analysis, and the development of synthetic oligonucleotides for therapeutic and diagnostic applications.


CAS Number 105931-57-5
Molecular Formula C47H54N5O8P
Purity ≥95%
Target DNA/RNA Synthesis
Storage -20°C
IUPAC Name N-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide
InChI InChI=1S/C47H54N5O8P/c1-32(2)52(33(3)4)61(58-28-14-27-48)60-41-29-43(51-30-34(5)44(50-46(51)54)49-45(53)35-15-10-8-11-16-35)59-42(41)31-57-47(36-17-12-9-13-18-36,37-19-23-39(55-6)24-20-37)38-21-25-40(56-7)26-22-38/h8-13,15-26,30,32-33,41-43H,14,28-29,31H2,1-7H3,(H,49,50,53,54)/t41-,42+,43+,61?/m0/s1
InChIKey AGMUHEZFYUECLW-QUZMAVINSA-N
SMILES CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)[C@H]3C[C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N

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