N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite

For research use only. Not for therapeutic Use.

  • CAT Number: L010777
  • CAS Number: 105931-57-5
  • Molecular Formula: C47H54N5O8P
  • Molecular Weight: 847.90
  • Purity: ≥95%
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N4-Benzoyl-2′-deoxy-5′-O-DMT-5-methylcytidine 3′-CE phosphoramidite(Cat No.:L010777)is a chemically modified nucleoside used in oligonucleotide synthesis. The N4-benzoyl and 5′-O-DMT (dimethoxytrityl) protective groups ensure stability during the synthesis process, while the 3′-CE (cyanoethyl) phosphoramidite group enables efficient incorporation into DNA strands. This modified nucleoside is particularly valuable for producing methylated DNA, which is important in studying epigenetic regulation and DNA-protein interactions. It is commonly used in research involving gene expression, DNA methylation analysis, and the development of synthetic oligonucleotides for therapeutic and diagnostic applications.


Catalog Number L010777
CAS Number 105931-57-5
Molecular Formula C47H54N5O8P
Purity ≥95%
Target DNA/RNA Synthesis
Storage -20°C
IUPAC Name N-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide
InChI InChI=1S/C47H54N5O8P/c1-32(2)52(33(3)4)61(58-28-14-27-48)60-41-29-43(51-30-34(5)44(50-46(51)54)49-45(53)35-15-10-8-11-16-35)59-42(41)31-57-47(36-17-12-9-13-18-36,37-19-23-39(55-6)24-20-37)38-21-25-40(56-7)26-22-38/h8-13,15-26,30,32-33,41-43H,14,28-29,31H2,1-7H3,(H,49,50,53,54)/t41-,42+,43+,61?/m0/s1
InChIKey AGMUHEZFYUECLW-QUZMAVINSA-N
SMILES CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)[C@H]3C[C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N

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