N6-Benzoyl-2’-deoxy-5’-O-DMT-cytidine 3’-CE Phosphoramidite

• CAT Number: R024238
• CAS Number: 98796-53-3
• Molecular Formula: C47H52N7O7P
• Molecular Weight: 857.94
• Purity: ≥95%
• Synonyms: N-Benzoyl-5’-O-[bis(4-methoxyphenyl)​phenylmethyl]​-2’-deoxy-adenosine ; 3’-[2-cyanoethyl N,​N-Bis(1-methylethyl)​phosphoramidite]; DMT-​dA(bz) Phosphoramidite
• Target: DNA/RNA Synthesis
• Storage: 3 years -20C powder
• IUPAC Name: N-[9-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]benzamide
• InChI: InChI=1S/C47H52N7O7P/c1-32(2)54(33(3)4)62(59-27-13-26-48)61-40-28-42(53-31-51-43-44(49-30-50-45(43)53)52-46(55)34-14-9-7-10-15-34)60-41(40)29-58-47(35-16-11-8-12-17-35,36-18-22-38(56-5)23-19-36)37-20-24-39(57-6)25-21-37/h7-12,14-25,30-33,40-42H,13,27-29H2,1-6H3,(H,49,50,52,55)/t40-,41+,42+,62?/m0/s1
• InChIKey: GGDNKEQZFSTIMJ-AKWFTNRHSA-N
• SMILES: CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=NC6=C5N=CN=C6NC(=O)C7=CC=CC=C7

N6-Benzoyl-2’-deoxy-5’-O-DMT-cytidine 3’-CE Phosphoramidite(Cat No.:R024238) is a complex compound used in the field of nucleic acid chemistry and DNA synthesis. Its mode of action involves serving as a phosphoramidite derivative, which is used in solid-phase synthesis to introduce the cytidine nucleotide into the growing DNA chain. The compound contains a benzoyl group on the N6 position of the cytidine base and a dimethoxytrityl (DMT) protecting group on the 5’-hydroxyl group of the deoxyribose sugar. Additionally, it has a 3′-CE (controlled-pore glass (CPG)-attached) modification to facilitate DNA synthesis. This reagent is crucial in automated DNA synthesis for various research and biotechnological applications, including the generation of custom oligonucleotides for molecular biology studies, gene synthesis, and diagnostics.