N6-Diazo-L-Fmoc-lysine

• CAT Number: M135151
• CAS Number: 159610-89-6
• Molecular Formula: C21H22N4O4
• Molecular Weight: 394.42
• Purity: ≥95%
• Synonyms: (2S)-6-azido-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
• InChI: InChI=1S/C21H22N4O4/c22-25-23-12-6-5-11-19(20(26)27)24-21(28)29-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19H,5-6,11-13H2,(H,24,28)(H,26,27)/t19-/m0/s1
• InChIKey: PJRFTUILPGJJIO-IBGZPJMESA-N
• SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@@H](CCCCN=[N+]=[N-])C(=O)O

N6-Diazo-L-Fmoc-lysine（Cat No.:M135151）is a modified form of L-lysine, where a diazo group is attached to the N6 position of the lysine side chain and an Fmoc (fluorenylmethoxycarbonyl) group is attached to the N-terminal amino group. The Fmoc group serves as a protective group during peptide synthesis, allowing selective removal under basic conditions. The diazo group is a reactive functional group, useful in chemical crosslinking and bioorthogonal reactions. N6-Diazo-L-Fmoc-lysine is utilized in peptide synthesis and protein engineering, where selective modification of lysine residues is required for functional studies or conjugation purposes.