For research use only. Not for therapeutic Use.
N6-Ethyladenosine is an adenosine derivative, acts as a Adenosine receptor agonist, with Kis of 4.9 and 4.7 nM for hA1AR and hA3AR, respectively[1].
N6-Ethyladenosine (Compound 28) exhibits more selectivity at hA1AR and hA3AR over hA2AR (Ki, 8900±770 nM)[1].
| Catalog Number | I019269 |
| CAS Number | 14357-08-5 |
| Synonyms | (2R,3R,4S,5R)-2-[6-(ethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol |
| Molecular Formula | C12H17N5O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C12H17N5O4/c1-2-13-10-7-11(15-4-14-10)17(5-16-7)12-9(20)8(19)6(3-18)21-12/h4-6,8-9,12,18-20H,2-3H2,1H3,(H,13,14,15)/t6-,8-,9-,12-/m1/s1 |
| InChIKey | SHXVYOLWYFZWKE-WOUKDFQISA-N |
| SMILES | CCNC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)O |
| Reference | [1]. Kimand SK, et al. Three-dimensional quantitative structure-activity relationship of nucleosides acting at the A3 adenosine receptor: analysis of binding and relative efficacy. J Chem Inf Model. 2007 May-Jun;47(3):1225-33. Epub 2007 Mar 6. |
