N6-Isopentenyladenosine

• CAT Number: R058681
• CAS Number: 7724-76-7
• Molecular Formula: C15H21N5O4
• Molecular Weight: 335.364
• Purity: ≥95%
• Synonyms: N-(3-Methyl-2-butenyl)-adenosine; 6-(3-Methyl-2-butenylamino)-9-β-D-ribofuranosylpurine; 6-(3-Methyl-2-butenylamino)-9-β-ribofuranosylpurine; 6-(3-Methyl-2-butenylamino)-β,D-ribofuranosylpurine; 6-(3-Methyl-2-butenylamino)purine riboside; 6-(γ,γ-Dime
• Target: Metabolic Enzyme/Protease
• Storage: -20°C
• IUPAC Name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(3-methylbut-2-enylamino)purin-9-yl]oxolane-3,4-diol
• InChI: InChI=1S/C15H21N5O4/c1-8(2)3-4-16-13-10-14(18-6-17-13)20(7-19-10)15-12(23)11(22)9(5-21)24-15/h3,6-7,9,11-12,15,21-23H,4-5H2,1-2H3,(H,16,17,18)/t9-,11-,12-,15-/m1/s1
• InChIKey: USVMJSALORZVDV-SDBHATRESA-N
• SMILES: CC(=CCNC1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)O)O)C

N6-Isopentenyladenosine (Cat.No:R058681) is a cytokinin growth regulator which can be produced endogenously by plants to direct differentiation of callus cells; investigated as an emerging anticancer drug; demonstrates the ability to induce cell cycle arest and apoptosis.

Reference

1.Castiglioni, S., Casati, S., Ottria, R., Ciuffreda, P., & A.M. Maier, J. (2013).
2.N6-Isopentenyladenosine and its analogue N6-Benzyladenosine induce cell cycle arrest and Apoptosis in bladder carcinoma T24 cells. Anti-Cancer Agents in Medicinal Chemistry, 13(4), 672–678.