For research use only. Not for therapeutic Use.
N6-Methyladenosine 5′-monophosphate disodium salt is an activator of glycogen phosphorylase b, with a Ka value of 22 µM[1]. N6-Methyladenosine 5′-monophosphate disodium salt is a non-competitive rat adenylate kinase II inhibitor[2].
| Catalog Number | I019231 |
| CAS Number | 81921-35-9 |
| Synonyms | disodium;[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(methylamino)purin-9-yl]oxolan-2-yl]methyl phosphate |
| Molecular Formula | C11H14N5Na2O7P |
| Purity | ≥95% |
| InChI | InChI=1S/C11H16N5O7P.2Na/c1-12-9-6-10(14-3-13-9)16(4-15-6)11-8(18)7(17)5(23-11)2-22-24(19,20)21;;/h3-5,7-8,11,17-18H,2H2,1H3,(H,12,13,14)(H2,19,20,21);;/q;2*+1/p-2/t5-,7-,8-,11-;;/m1../s1 |
| InChIKey | HFOKUKRAZPHTHH-LYYWGVPGSA-L |
| SMILES | CNC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])[O-])O)O.[Na+].[Na+] |
| Reference | [1]. Groner Y, et al. 5′-Capping structures of Artemia salina mRNA and the translational inhibition by cap analogs. Eur J Biochem. 1976 Dec;71(1):281-93. [2]. Hai TT, et al. Species- or isozyme-specific enzyme inhibitors. 9. Selective effects in inhibitions of rat pyruvate kinase isozymes by adenosine 5′-diphosphate derivatives. J Med Chem. 1982 Oct;25(10):1184-8. |
