N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride

• CAT Number: R053070
• CAS Number: 42267-27-6
• Molecular Formula: C9H11F3N2O4
• Molecular Weight: 268.192
• Purity: ≥95%
• Synonyms: N-[4-[(4S)-2,5-Dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoroacetamide; (S)-N-[4-(2,5-Dioxo-4-oxazolidinyl)butyl]-2,2,2-trifluoroacetamide; Lys(Tfa)-NCA
• Storage: -20°C
• IUPAC Name: N-[4-[(4S)-2,5-dioxo-1,3-oxazolidin-4-yl]butyl]-2,2,2-trifluoroacetamide
• InChI: InChI=1S/C9H11F3N2O4/c10-9(11,12)7(16)13-4-2-1-3-5-6(15)18-8(17)14-5/h5H,1-4H2,(H,13,16)(H,14,17)/t5-/m0/s1
• InChIKey: KWNIHCJDDYRQFW-YFKPBYRVSA-N
• SMILES: C(CCNC(=O)C(F)(F)F)CC1C(=O)OC(=O)N1

N6-Trifluoroacetyl-L-lysine N-carboxyanhydride is a specialized chemical used in peptide synthesis. It is derived from L-lysine and contains a trifluoroacetyl group along with a carboxyanhydride functional group. This compound serves as a versatile building block for introducing trifluoroacetyl-modified lysine residues into peptides during solid-phase peptide synthesis. The trifluoroacetyl group can enhance peptide stability and alter biological activity. N6-Trifluoroacetyl-L-lysine N-carboxyanhydride is valuable in pharmaceutical research for developing peptide-based drugs and probes with tailored properties.