For research use only. Not for therapeutic Use.
N6F11 is an inducer of ferroptosis. N6F11 is bound to the RING domain of the E3 ubiquitin ligase tripartite motif containing 25 (TRIM25) in cancer cells to trigger TRIM25-mediated K48-linked ubiquitination of glutathione peroxidase 4 (GPX4), resulting in proteasomal degradation.
| Catalog Number | I047371 |
| CAS Number | 851398-76-0 |
| Molecular Formula | C13H8Cl2N2OS |
| Purity | ≥95% |
| Reference | [1] Li J, et al. Sci Transl Med. 2023 Nov;15(720):eadg3049. |
