N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium

• CAT Number: I044169
• CAS Number: 75252-10-7
• Molecular Formula: C21H35N12O17P3
• Molecular Weight: 820.49
• Purity: ≥95%
• Synonyms: diazanium;[[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] phosphate
• InChI: InChI=1S/C21H29N10O17P3.2H3N/c1-29-6-31(17-10(29)18(36)28-21(23)27-17)20-14(35)12(33)8(46-20)3-44-50(39,40)48-51(41,42)47-49(37,38)43-2-7-11(32)13(34)19(45-7)30-5-26-9-15(22)24-4-25-16(9)30;;/h4-8,11-14,19-20,32-35H,2-3H2,1H3,(H7-,22,23,24,25,27,28,36,37,38,39,40,41,42);2*1H3/t7-,8-,11-,12-,13-,14-,19-,20-;;/m1../s1
• InChIKey: VDIIAVSSPGYJCD-VEQUCWRQSA-N
• SMILES: CN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O.[NH4+].[NH4+]

N7-Methyl-guanosine-5′-triphosphate-5′-adenosine (m7GpppA) diammonium is a dinucleotide cap analog that can be used for in vitro RNA transcription[1].

Reference

[1]. Young-Min Lee. Compositions and methods for zika virus characterization and vaccine development. WO2019204654A1.