For research use only. Not for therapeutic Use.
Nab-Paclitaxel(CAT: I040975) (Nanoparticle Albumin-Bound Paclitaxel) is a novel formulation of Paclitaxel, a widely used microtubule-stabilizing chemotherapy agent. By binding to albumin nanoparticles, this formulation enhances solubility, reduces the need for toxic solvents like Cremophor EL, and improves drug delivery to tumors via albumin-mediated transcytosis. Nab-Paclitaxel promotes microtubule stabilization, preventing cancer cell division and inducing apoptosis. It is FDA-approved for breast cancer, non-small cell lung cancer (NSCLC), and pancreatic cancer. Given its mechanism and clinical relevance, Nab-Paclitaxel is most relevant to Cancer Disease Research, particularly in studying improved drug delivery systems and chemotherapy resistance in solid tumors.
Catalog Number | I040975 |
Purity | ≥95% |