Nadifloxacin-d9

• CAT Number: R032842
• CAS Number: NA
• Molecular Formula: C₁₉H₁₂D₉FN₂O₄
• Molecular Weight: 369.43
• Purity: ≥95%
• Synonyms: 9-Fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic Acid-d9; Jinofloxacin-d9; OPC-7251-d9; Acuatim-d9
• Storage: -20°C
• IUPAC Name: 7-fluoro-12-methyl-8-(2,2,3,3,4,5,5,6,6-nonadeuterio-4-hydroxypiperidin-1-yl)-4-oxo-1-azatricyclo[7.3.1.05,13]trideca-2,5,7,9(13)-tetraene-3-carboxylic acid
• InChI: InChI=1S/C19H21FN2O4/c1-10-2-3-12-16-13(18(24)14(19(25)26)9-22(10)16)8-15(20)17(12)21-6-4-11(23)5-7-21/h8-11,23H,2-7H2,1H3,(H,25,26)/i4D2,5D2,6D2,7D2,11D
• InChIKey: JYJTVFIEFKZWCJ-LEKAFREJSA-N
• SMILES: [2H]C1(C(N(C(C(C1([2H])O)([2H])[2H])([2H])[2H])C2=C(C=C3C4=C2CCC(N4C=C(C3=O)C(=O)O)C)F)([2H])[2H])[2H]

Nadifloxacin-d9 is a deuterium-labeled version of nadifloxacin, a topical fluoroquinolone antibiotic used to treat bacterial infections such as acne. The deuterium labeling enhances its application in pharmacokinetic studies and analytical chemistry by providing better sensitivity and accuracy in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. This labeled compound helps in tracking the drug’s metabolism, distribution, and excretion in the body. It also aids in understanding drug interactions and optimizing formulations by offering precise data on the drug’s behavior in biological systems.