For research use only. Not for therapeutic Use.
Agonist for κ3 opioid receptors; antagonist for ORL1 and μ opioid receptors
| Catalog Number | M017535 |
| CAS Number | 119630-94-3 |
| Molecular Formula | C26H27N3O4 |
| Purity | ≥95% |
| IUPAC Name | N-[(E)-[(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ylidene]amino]benzamide |
| InChI | InChI=1S/C26H27N3O4/c1-2-13-29-14-12-25-21-17-8-9-19(30)22(21)33-23(25)18(10-11-26(25,32)20(29)15-17)27-28-24(31)16-6-4-3-5-7-16/h2-9,20,23,30,32H,1,10-15H2,(H,28,31)/b27-18+/t20-,23+,25+,26-/m1/s1 |
| SMILES | C=CCN1CC[C@]23[C@@H]4/C(=N/NC(=O)C5=CC=CC=C5)/CC[C@]2([C@H]1CC6=C3C(=C(C=C6)O)O4)O |
| Reference | MA Gistrak et al. Pharmacological actions of a novel mixed opiate agonist/antagonist: Naloxone benzoylhydrazone. J. Pharmacol. Exp. Ther. 1989, 251, 469-476.
D Paul et al. Naloxone benzoylhydrazone (NalBzoH) analgesia. J. Pharmacol. Exp. Ther. 1990, 255, 769-774. |
