Nangibotide TFA

• CAT Number: I043952
• Molecular Formula: C56H83F3N14O24S2
• Molecular Weight: 1457.46
• Purity: ≥95%

Nangibotide TFA is a TREM-1 receptor inhibitor that can modulate innate immune response. Nangibotide TFA can reduce systemic and in situ inflammatory reaction in rodent models of myocardial ischaemia-reperfusion[1].

Reference

[1]. Cuvier V, et, al. A first-in-man safety and pharmacokinetics study of nangibotide, a new modulator of innate immune response through TREM-1 receptor inhibition. Br J Clin Pharmacol. 2018 Oct;84(10):2270-2279.
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