Narciclasine

• CAT Number: I003024
• CAS Number: 29477-83-6
• Molecular Formula: C14H13NO7
• Molecular Weight: 307.25
• Purity: ≥95%
• Synonyms: (2S,3R,4S,4aR)-2,3,4,7-tetrahydroxy-3,4,4a,5-tetrahydro-2H-[1,3]dioxolo[4,5-j]phenanthridin-6-one
• Target: TGF-beta/Smad
• Solubility: DMSO > 10 mg.mL
• Storage: Store at -20°C
• IUPAC Name: C1OC2=C(O1)C(=C3C(=C2)C4=C[C@@H]([C@H]([C@H]([C@@H]4NC3=O)O)O)O)O
• InChI: InChI=1S/C14H13NO7/c16-6-1-5-4-2-7-13(22-3-21-7)11(18)8(4)14(20)15-9(5)12(19)10(6)17/h1-2,6,9-10,12,16-19H,3H2,(H,15,20)/t6-,9+,10+,12-/m0/s1
• InChIKey: LZAZURSABQIKGB-AEKGRLRDSA-N
• SMILES: OC1=C(C(N[C@]2([H])C3=C[C@H](O)[C@@H](O)[C@H]2O)=O)C3=CC4=C1OCO4

Narciclasine(CAT: I003024) is a naturally occurring alkaloid with potent anti-tumor and anti-inflammatory properties, derived from plants in the Amaryllidaceae family. It functions as an inhibitor of protein synthesis by targeting the eukaryotic elongation factor (eEF1A), making it a valuable tool for studying cancer cell proliferation and apoptosis. Narciclasine also exhibits neuroprotective effects, contributing to research in neurodegenerative diseases. Its high purity and reliability make it suitable for in vitro and in vivo experiments. Narciclasine supports advanced research in oncology, inflammation, and neurobiology, aiding the development of novel therapeutic strategies.