Naringin

For research use only. Not for therapeutic Use.

  • CAT Number: I000160
  • CAS Number: 10236-47-2
  • Molecular Formula: C27H32O14
  • Molecular Weight: 580.50
  • Purity: ≥95%
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Naringin(Cat No.:I000160)is a natural flavonoid glycoside primarily found in grapefruits and other citrus fruits, known for its antioxidant, anti-inflammatory, and cholesterol-lowering properties. It exerts beneficial effects by neutralizing free radicals, reducing oxidative stress, and supporting cardiovascular health. Additionally, Naringin has been studied for its potential in managing metabolic disorders, including diabetes and obesity, by enhancing insulin sensitivity and modulating lipid metabolism. Its bitter flavor contributes to the distinct taste of grapefruit, while its broad bioactivity makes Naringin a promising compound in nutraceuticals and functional food development.


Catalog Number I000160
CAS Number 10236-47-2
Synonyms

NSC 5548

Molecular Formula C27H32O14
Purity ≥95%
Target P450
Solubility DMSO:116 mg/mL (199.81 mM); Ethanol: 2 mg/mL (3.44 mM); Water: <1 mg/mL (<1 mM)
Storage 3 years -20C powder
IUPAC Name (2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
InChI InChI=1S/C27H32O14/c1-10-20(32)22(34)24(36)26(37-10)41-25-23(35)21(33)18(9-28)40-27(25)38-13-6-14(30)19-15(31)8-16(39-17(19)7-13)11-2-4-12(29)5-3-11/h2-7,10,16,18,20-30,32-36H,8-9H2,1H3/t10-,16-,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1
InChIKey DFPMSGMNTNDNHN-ZPHOTFPESA-N
SMILES C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=CC(=C4C(=O)C[C@H](OC4=C3)C5=CC=C(C=C5)O)O)CO)O)O)O)O)O
Reference

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<br>[1]. Ueng YF, Chang YL et al. In vitro and in vivo effects of naringin on cytochrome P450-dependent monooxygenase in mouse liver. Life Sci, 1999, 65(24):2591-602.
<br>[2]. Merve Bacanl, et al. The antioxidant and antigenotoxic properties of citrus phenolics limonene and naringin. Food and Chemical Toxicology, July 2015, Pages 160-170
<br>[3]. CAMILA A. CAMARGO et al. Naringin Inhibits Tumor Growth and Reduces Interleukin-6 and Tumor Necrosis Factor α Levels in Rats with Walker 256 Carcinosarcoma. Anticancer Res, 2012 Jan, 32(1):129-33.
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