For research use only. Not for therapeutic Use.
NAT is an initial hit of NAMPT activator. NAMPT is the rate-limiting enzyme in the NAD salvage pathway, which makes it an attractive target for the research of many diseases associated with NAD exhaustion such as neurodegenerative diseases[1].
| Catalog Number | I044041 |
| CAS Number | 831243-31-3 |
| Synonyms | 2-(2-tert-butylphenoxy)-N-(4-hydroxyphenyl)acetamide |
| Molecular Formula | C18H21NO3 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H21NO3/c1-18(2,3)15-6-4-5-7-16(15)22-12-17(21)19-13-8-10-14(20)11-9-13/h4-11,20H,12H2,1-3H3,(H,19,21) |
| InChIKey | RUNXUUCDTNJFME-UHFFFAOYSA-N |
| SMILES | CC(C)(C)C1=CC=CC=C1OCC(=O)NC2=CC=C(C=C2)O |
| Reference | [1]. Wang L, et al. Optimization of NAMPT activators to achieve in vivo neuroprotective efficacy [published online ahead of print, 2022 Mar 16]. Eur J Med Chem. 2022;236:114260. |
