Nateglinide-d5

• CAT Number: R003999
• CAS Number: 1227666-13-8
• Molecular Formula: C19H27NO3
• Molecular Weight: 322.46
• Purity: ≥95%
• Synonyms: N-[[trans-4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine-d5; A 4166; AY 4166-d5; D-Nateglinide-d5; DJN 608-d5; Fastic-d5; Glinate-d5; Natelide-d5; SDZ-DJN 608-d5; Senaglinide-d5; Starlix-d5; Starlix DS-d5; Starsis-d5;?
• Storage: -20°C
• IUPAC Name: (2R)-3-(2,3,4,5,6-pentadeuteriophenyl)-2-[(4-propan-2-ylcyclohexanecarbonyl)amino]propanoic acid
• InChI: InChI=1S/C19H27NO3/c1-13(2)15-8-10-16(11-9-15)18(21)20-17(19(22)23)12-14-6-4-3-5-7-14/h3-7,13,15-17H,8-12H2,1-2H3,(H,20,21)(H,22,23)/t15?,16?,17-/m1/s1/i3D,4D,5D,6D,7D
• InChIKey: OELFLUMRDSZNSF-ZBRYERADSA-N
• SMILES: [2H]C1=C(C(=C(C(=C1[2H])[2H])C[C@H](C(=O)O)NC(=O)C2CCC(CC2)C(C)C)[2H])[2H]

Nateglinide-d5（Cat No.:R003999） is a deuterated version of Nateglinide, an antidiabetic medication, featuring five deuterium atoms that enhance its analytical tracing capabilities in pharmacokinetic studies. This isotopic enhancement improves the stability and minimizes the metabolic degradation of the compound, facilitating more accurate assessments of its pharmacological profile. Nateglinide-d5 is crucial for research into drug interactions and the effects of metabolic variations on drug efficacy. It is primarily used in the management of type 2 diabetes, where it helps in understanding the drug’s action in reducing postprandial blood glucose levels.