For research use only. Not for therapeutic Use.
NCGC00262650 is a potent apical membrane antigen 1-rhoptry neck protein 2 (AMA1-RON2) interaction inhibitor. NCGC00262650 can block entry of merozoites into red blood cells[1].
| Catalog Number | I033104 |
| CAS Number | 344359-25-7 |
| Synonyms | 7-cyclopentyl-5-(4-methoxyphenyl)pyrrolo[2,3-d]pyrimidin-4-amine |
| Molecular Formula | C18H20N4O |
| Purity | ≥95% |
| InChI | InChI=1S/C18H20N4O/c1-23-14-8-6-12(7-9-14)15-10-22(13-4-2-3-5-13)18-16(15)17(19)20-11-21-18/h6-11,13H,2-5H2,1H3,(H2,19,20,21) |
| InChIKey | BRUSFAZPHIPJRR-UHFFFAOYSA-N |
| SMILES | COC1=CC=C(C=C1)C2=CN(C3=NC=NC(=C23)N)C4CCCC4 |
| Reference | [1]. Srinivasan P, et, al. Disrupting malaria parasite AMA1-RON2 interaction with a small molecule prevents erythrocyte invasion. Nat Commun. 2013;4:2261. |
