For research use only. Not for therapeutic Use.
NCRW0005-F05（Cat No.:I042951）is a potent antagonist of the orphan G-protein coupled receptor GPR139, exhibiting an IC50 value of 0.21 μM. GPR139 is predominantly expressed in the central nervous system and is implicated in various physiological processes. The antagonistic properties of NCRW0005-F05 make it a valuable tool for studying GPR139 pharmacology, especially when used in conjunction with GPR139 agonists like JNJ-63533054. Research utilizing NCRW0005-F05 has potential applications in exploring treatments for conditions such as diabetes, obesity, and Parkinson’s disease.
| CAS Number | 342779-66-2 |
| Synonyms | 3,3-difluoro-4-(4-methoxyphenyl)-1-phenylazetidin-2-one |
| Molecular Formula | C16H13F2NO2 |
| Purity | ≥95% |
| IUPAC Name | 3,3-difluoro-4-(4-methoxyphenyl)-1-phenylazetidin-2-one |
| InChI | InChI=1S/C16H13F2NO2/c1-21-13-9-7-11(8-10-13)14-16(17,18)15(20)19(14)12-5-3-2-4-6-12/h2-10,14H,1H3 |
| InChIKey | AIIIYUSGINMZMS-UHFFFAOYSA-N |
| SMILES | COC1=CC=C(C=C1)C2C(C(=O)N2C3=CC=CC=C3)(F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
