Necrostatin-1 (inactive control)

• CAT Number: R066923
• CAS Number: 64419-92-7
• Molecular Formula: C12H11N3OS
• Molecular Weight: 245.30
• Purity: ≥95%
• Synonyms: 5-(1H-indol-3-ylmethyl)-2-sulfanylideneimidazolidin-4-one
• InChI: InChI=1S/C12H11N3OS/c16-11-10(14-12(17)15-11)5-7-6-13-9-4-2-1-3-8(7)9/h1-4,6,10,13H,5H2,(H2,14,15,16,17)
• InChIKey: MPLRRPKKFHUEEL-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(=CN2)CC3C(=O)NC(=S)N3

Necrostatin-1 (Nec-1) (inactive control) is an inactive analog of Necrostatin-1 (HY-15760). Necrostatin-1 is a potent necroptosis inhibitor[1].

Reference

[1]. Degterev A, et al. Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol. 2008 May;4(5):313-21.
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