Necrostatin-34 (Nec-34)

• CAT Number: I047375
• CAS Number: 375835-43-1
• Molecular Formula: C18H16N4O2S2
• Molecular Weight: 384.48
• Purity: ≥95%
• Storage: 3 years -20°C powder
• SMILES: CC1=CC=C(C=C1)C2CC(=O)NC(=C2C#N)SCC(=O)NC3=NC=CS3

Necrostatin-34 (Nec-34) is a small molecule inhibitor of RIPK1 kinase with an IC50 of 0.13 μM in L929 cells.

Reference

[1] Huyan Meng, et al. Cell Discov . 2021 Jun 1;7(1):41.