Nefiracetam

• CAT Number: I004843
• CAS Number: 77191-36-7
• Molecular Formula: C14H18N2O2
• Molecular Weight: 246.3
• Purity: ≥95%
• Synonyms: N-(2,6-dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide
• Target: GABA Receptor
• Solubility: DMSO:50 mg/mL; Water 5 mg/mL
• Storage: 3 years -20℃ powder
• InChI: InChI=1S/C14H18N2O2/c1-10-5-3-6-11(2)14(10)15-12(17)9-16-8-4-7-13(16)18/h3,5-6H,4,7-9H2,1-2H3,(H,15,17)
• InChIKey: NGHTXZCKLWZPGK-UHFFFAOYSA-N
• SMILES: CC1=C(C(=CC=C1)C)NC(=O)CN2CCCC2=O

Nefiracetam (Cat.No:I004843) is a nootropic compound belonging to the racetam family. It exhibits neuroprotective and cognition-enhancing properties. Nefiracetam is thought to modulate various neurotransmitter systems, including glutamate, acetylcholine, and GABA. It has shown potential for improving memory, learning, and cognitive function, and is being studied for its therapeutic applications in neurodegenerative disorders and cognitive impairments.

Reference

[1]. Nishizaki, T., et al., Nefiracetam modulates acetylcholine receptor currents via two different signal transduction pathways. Mol Pharmacol, 1998. 53(1): p. 1-5.
[2]. Shiotani, T., et al., Anticonvulsant actions of nefiracetam on epileptic EL mice and their relation to peripheral-type benzodiazepine receptors. Brain Res, 2000. 859(2): p. 255-61.
[3]. Sakurai, T., et al., Effects of N-(2,6-dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide (DM-9384) on learning and memory in rats. Jpn J Pharmacol, 1989. 50(1): p. 47-53.