Nek2/Hec1-IN-2

For research use only. Not for therapeutic Use.

  • CAT Number: I041079
  • CAS Number: 544416-00-4
  • Molecular Formula: C16H14N4OS
  • Molecular Weight: 310.37
  • Purity: ≥95%
Inquiry Now

Nek2/Hec1-IN-2 (Compound 14) is an inhibitor of Nek2/Hec1. Nek2/Hec1-IN-2 inhibits cancer cell proliferation with IC50 >25 μM[1].


Catalog Number I041079
CAS Number 544416-00-4
Synonyms

N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]pyrazine-2-carboxamide

Molecular Formula C16H14N4OS
Purity ≥95%
InChI InChI=1S/C16H14N4OS/c1-10-3-4-12(11(2)7-10)14-9-22-16(19-14)20-15(21)13-8-17-5-6-18-13/h3-9H,1-2H3,(H,19,20,21)
InChIKey GANRESSEAJEWSH-UHFFFAOYSA-N
SMILES CC1=CC(=C(C=C1)C2=CSC(=N2)NC(=O)C3=NC=CN=C3)C
Reference

[1]. Qiu XL, et al. Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analogues. J Med Chem. 2009 Mar 26;52(6):1757-67.
 [Content Brief]

Request a Quote