For research use only. Not for therapeutic Use.
Nemonoxacin-d3, a premium pharmaceutical research compound designed for advanced antibacterial and antimicrobial studies. As a deuterated analog of Nemonoxacin, it offers enhanced stability and improved pharmacokinetic properties. Nemonoxacin-d3 is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel antibacterial therapies. Trusted by leading laboratories, Nemonoxacin-d3 is your go-to solution for cutting-edge antibacterial research. Unlock new possibilities in infection treatment with Nemonoxacin-d3, where innovation meets reliability.
| Catalog Number | S000205 |
| Molecular Formula | C20H22D3N3O4 |
| Purity | ≥95% |
| Target | Bacterial |
| IUPAC Name | 7-[(3S,5S)-3-amino-5-methylpiperidin-1-yl]-1-cyclopropyl-4-oxo-8-(trideuteriomethoxy)quinoline-3-carboxylic acid |
| InChI | InChI=1S/C20H25N3O4/c1-11-7-12(21)9-22(8-11)16-6-5-14-17(19(16)27-2)23(13-3-4-13)10-15(18(14)24)20(25)26/h5-6,10-13H,3-4,7-9,21H2,1-2H3,(H,25,26)/t11-,12-/m0/s1/i2D3 |
| InChIKey | AVPQPGFLVZTJOR-IYZCKYNTSA-N |
| SMILES | [2H]C([2H])([2H])OC1=C(C=CC2=C1N(C=C(C2=O)C(=O)O)C3CC3)N4C[C@H](C[C@@H](C4)N)C |
| Reference | [1]. Adam HJ, et al. In vitro activity of nemonoxacin, a novel nonfluorinated quinolone, against 2,440 clinical isolates. Antimicrob Agents Chemother. 2009 Nov;53(11):4915-20. [2]. Li CR, et al. In vivo antibacterial activity of nemonoxacin, a novel non-fluorinated quinolone. J Antimicrob Chemother. 2010 Nov;65(11):2411-5. [3]. Lauderdale TL, et al. Comparative in vitro activities of nemonoxacin (TG-873870), a novel nonfluorinated quinolone, and other quinolones against clinical isolates. Antimicrob Agents Chemother. 2010 Mar;54(3):1338-42. [4]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. |
