NEOMYCIN B

• CAT Number: M068249
• CAS Number: 119-04-0
• Molecular Formula: C23H46N6O13
• Molecular Weight: 614.65
• Purity: ≥95%
• Target: Bacterial
• Storage: -20°C
• IUPAC Name: (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol
• InChI: InChI=1S/C23H46N6O13/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22/h5-23,30-36H,1-4,24-29H2/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1
• InChIKey: PGBHMTALBVVCIT-VCIWKGPPSA-N
• SMILES: C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O[C@@H]4[C@@H]([C@H]([C@@H]([C@@H](O4)CN)O)O)N)O)O)N

Neomycin B（Cat No.:M068249）is an aminoglycoside antibiotic used primarily for its broad-spectrum antibacterial activity. It is effective against a range of Gram-negative and Gram-positive bacteria. Neomycin B works by binding to bacterial ribosomes, inhibiting protein synthesis, which leads to bacterial cell death. It is often used in topical and oral applications for treating skin infections, eye infections, and gastrointestinal disorders. Although it exhibits strong antibacterial properties, Neomycin B can cause nephrotoxicity and ototoxicity, limiting its use in systemic applications. It is commonly found in combination with other antibiotics for enhanced therapeutic efficacy.

Reference

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