Neomycin sulfate

For research use only. Not for therapeutic Use.

  • CAT Number: A000999
  • CAS Number: 1405-10-3
  • Molecular Formula: C₂₃H₄₆N₆O₁₃·3H₂SO₄
  • Molecular Weight: 908.90
  • Purity: ≥95%
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Neomycin sulfate(Cat No.:A000999)is an aminoglycoside antibiotic used primarily for the treatment of bacterial infections. It works by inhibiting protein synthesis in bacteria, leading to their death. Neomycin sulfate is effective against a broad spectrum of gram-negative and gram-positive bacteria, making it useful in treating skin, eye, and ear infections. It is also employed in preoperative bowel cleansing. However, it is not typically administered orally due to its poor absorption, and its systemic use is limited by potential nephrotoxicity and ototoxicity.


Catalog Number A000999
CAS Number 1405-10-3
Synonyms

NA

Molecular Formula C₂₃H₄₆N₆O₁₃·3H₂SO₄
Purity ≥95%
Storage 3 years -20C powder
Reference

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Davis, Bernard D. /Mechanism of Bactericidal Action of Aminoglycosides./Microbiological Reviews 51.3 (1987): 341-50.</p>
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Dai S., Zheng P., Marmey P., Zhang S., Tian W., Chen S., Beachy R.N. and Fauquet C, 2001, Comparative analysis of transgenic rice plants obtained by Agrobacterium-mediated transformation and particle bombardment. Molecular Breeding 7: 25&ndash;33, 2001.</p>
<p>
Tsuji, Kiyoshi, and John H. Robertson. /Comparative Study of Responses to Neomycins B and C by Microbiological and Gas-Liquid Chromatographic Assay Methods./Applied Microbiology 18.3 (1969): 396-98. Nih.gov. Web. 23 Oct. 2013.</p>
<p>
Yuan, LingLing, and HongPing Wei. /Rapid Analysis of Native Neomycin Components on a Portable Capillary Electrophoresis System with Potential Gradient Detection./Analytical and Bioanalytical Chemistry 385.8 (2006): 1575-579. Nih.gov. Web. 23 Oct. 2013.</p>
<p>
Robertson, John H. /Antimicrobial Activity of Neomycin C Against Staphylococcus Epidermidis./ Applied Microbiology 22.6 (1971): 1164-165. Nih.gov. Web. 23 Oct. 2013.</p>
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