For research use only. Not for therapeutic Use.
Neoseptin-3 (Cat.No:I011965) is a synthetic peptide with antimicrobial properties. It belongs to the neoseptin family of peptides and exhibits broad-spectrum activity against various bacteria, including drug-resistant strains. Neoseptin-3 shows potential as a therapeutic agent for the treatment of bacterial infections and may contribute to the development of novel antimicrobial strategies.
| Catalog Number | I011965 |
| CAS Number | 1622863-21-1 |
| Synonyms | Neoseptin-3;(alphaS)-alpha-[[4-Amino-3-[2-(4-hydroxyphenyl)ethyl]benzoyl]amino]-benzenebutanoic acid tert-butyl ester |
| Molecular Formula | C29H34N2O4 |
| Purity | ≥95% |
| Target | Toll-like Receptor (TLR) |
| Solubility | Soluble in DMSO |
| Storage | Store at 0-8 °C |
| InChI | InChI=1S/C29H34N2O4/c1-29(2,3)35-28(34)26(18-12-20-7-5-4-6-8-20)31-27(33)23-14-17-25(30)22(19-23)13-9-21-10-15-24(32)16-11-21/h4-8,10-11,14-17,19,26,32H,9,12-13,18,30H2,1-3H3,(H,31,33)/t26-/m0/s1 |
| InChIKey | OACODUCFPHHCIH-SANMLTNESA-N |
| SMILES | O=C(OC(C)(C)C)[C@@H](NC(C1=CC=C(N)C(CCC2=CC=C(O)C=C2)=C1)=O)CCC3=CC=CC=C3 |
| Reference | </br>1: Wang Y, Su L, Morin MD, Jones BT, Whitby LR, Surakattula MM, Huang H, Shi H, Choi JH, Wang KW, Moresco EM, Berger M, Zhan X, Zhang H, Boger DL, Beutler B. TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):E884-93. doi: 10.1073/pnas.1525639113. Epub 2016 Feb 1. Erratum in: Proc Natl Acad Sci U S A. 2016 Apr 5;113(14 ):E2096. PubMed PMID: 26831104; PubMed Central PMCID: PMC4763747.</br></br> |
