For research use only. Not for therapeutic Use.
Neostigmine methyl sulfate (Cat No.: I003861) is a reversible inhibitor of acetylcholinesterase (AChE), which cannot penetrate the blood-brain barrier, and is used for the treatment of myasthenia gravis. Neostigmine methyl sulfate can also be used as a pharmaceutical raw material, mainly as an anticholinergic drug.
| Catalog Number | I003861 |
| CAS Number | 51-60-5 |
| Molecular Formula | C13H22N2O6S |
| Purity | ≥95% |
| Target | Cholinesterase (ChE) |
| Solubility | 10 mM in DMSO, 10 mM in H2O |
| Storage | -20°C |
| IUPAC Name | [3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium;methyl sulfate |
| InChI | InChI=1S/C12H19N2O2.CH4O4S/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5;1-5-6(2,3)4/h6-9H,1-5H3;1H3,(H,2,3,4)/q+1;/p-1 |
| InChIKey | OSZNNLWOYWAHSS-UHFFFAOYSA-M |
| SMILES | CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.COS(=O)(=O)[O-] |
| Reference | 1:Yao Xue Xue Bao. 1982 Jul;17(7):534-9. [Applications of A C oscillopolarographic titration in pharmaceutical analysis. I. Titration of neostigmine methyl sulfate injection with sodium tetraphenylborate].Huang TH,Pan DH,Gao H, PMID: 7180485 |
