Nervonic Acid

• CAT Number: R032486
• CAS Number: 506-37-6
• Molecular Formula: C24H46O2
• Molecular Weight: 366.63
• Purity: ≥95%
• Synonyms: (15Z)-15-Tetracosenoic acid; (15Z)-Tetracosenoic acid; (Z)-15-Tetracosenoic acid; ?Nevonic acid; Selacholeic acid; cis-15-Tetracosenoic acid
• Target: NF-κB
• Storage: -20°C
• IUPAC Name: (Z)-tetracos-15-enoic acid
• InChI: InChI=1S/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9-
• InChIKey: GWHCXVQVJPWHRF-KTKRTIGZSA-N
• SMILES: CCCCCCCCC=CCCCCCCCCCCCCCC(=O)O

Nervonic acid（Cat No.:R032486）, is a long-chain monounsaturated fatty acid with 24 carbon atoms and one double bond. It is found in various plant and animal sources, particularly in nerve tissues and myelin sheaths, where it plays a crucial role in maintaining nervous system health and function. Nervonic acid is associated with potential benefits for cognitive health and has been investigated for its role in managing conditions like multiple sclerosis. It is available in dietary supplements and is sometimes used as a component in infant formula to support neural development.

Reference

1. J. Sargent, K. Coupland, and R. Wilson “Nervonic acid and demyelinating disease” Medical Hypotheses, vol. 42 pp. 237-242, 19942. G. Shearer et al. “Plasma Fatty Acids in Chronic Kidney Disease: Nervonic Acid Predicts Mortality” J Ren Nutr. (2011) doi:10.1053/j.jrn.2011.05.0053. F. Babin et al. “Nervonic acid in red blood cell sphingomyelin in premature infants: An index of myelin maturation?” Lipids, vol. 28 pp. 627-630, 19934. J. Chen et al. “Dietary patterns and blood fatty acid composition in children with attention-deficit hyperactivity disorder in Taiwan” The Journal of Nutritional Biochemistry, vol. 15 pp. 467-472, 20045. N. Kasai et al. “Three-Dimensional Structural Model Analysis of the Binding Site of an Inhibitor, Nervonic Acid, of Both DNA Polymerase beta and HIV-1 Reverse Transcriptase” J. Biochem, vol. 132 pp. 819-828, 2002