For research use only. Not for therapeutic Use.
Netupitant-d6 (CAS: 2070015-31-3), a premium pharmaceutical research compound designed for advanced studies in antiemetic and oncology research. As a deuterated analog of Netupitant, it offers enhanced stability and improved pharmacokinetic properties. Netupitant-d6 is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel therapies for chemotherapy-induced nausea and vomiting (CINV). Trusted by leading laboratories, Netupitant-d6 is your go-to solution for cutting-edge antiemetic research. Unlock new possibilities in nausea and vomiting treatment with Netupitant-d6, where innovation meets reliability.
| Catalog Number | S000137 |
| CAS Number | 2070015-31-3 |
| Molecular Formula | C30H26D6F6N4O |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| IUPAC Name | 2-[3,5-bis(trifluoromethyl)phenyl]-3,3,3-trideuterio-N-methyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl]-2-(trideuteriomethyl)propanamide |
| InChI | InChI=1S/C30H32F6N4O/c1-19-8-6-7-9-23(19)24-17-26(40-12-10-38(4)11-13-40)37-18-25(24)39(5)27(41)28(2,3)20-14-21(29(31,32)33)16-22(15-20)30(34,35)36/h6-9,14-18H,10-13H2,1-5H3/i2D3,3D3 |
| InChIKey | WAXQNWCZJDTGBU-XERRXZQWSA-N |
| SMILES | [2H]C([2H])([2H])C(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)(C(=O)N(C)C2=CN=C(C=C2C3=CC=CC=C3C)N4CCN(CC4)C)C([2H])([2H])[2H] |
| Reference | [1]. Hoffmann T, et al. Design and synthesis of a novel, achiral class of highly potent and selective, orally active neurokinin-1 receptor antagonists. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1362-5. |
